im in the same boat as you, been using PCs since the womb and first-time osx user for eqmac. unfortunately osx is pretty fucking terrible, although most on this forum will tell you otherwise =p
once you buy your mac and set it up, here are some tips from a fellow convertee.
1) play with a PC keyboard. mac keyboards have all the modifier buttons in the wrong places and the function keys are only half the size of normal keys. no, don't bother trying to rewire your brain - just play with a PC keyboard. (by default flag = command)
2) dont use a mighty mouse. your new mac will come with a mac mouse. it sucks so bad you will want to cry within 5 minutes of using it, so save yourself the trouble and throw it in the garbage disposal.
3) dont use stock mouse drivers. download OSX ones from the manufactures website, if at all available. if it isn't available (or you did download them and your mouse still sucks complete ass) download a program called USBOverdrive and toy with the settings. (know that your mouse will never be as fast and snappy as it is on PC. welcome to osx)
4) most hotkeys on PC that are control+whatever are command+whatever on mac (aka cut, copy, paste, undo, find, etc). download a program called DoubleCommand to duplicate command/flag to control. (this will essentially remove control completely, but trust me it has absolutely no use anyway)
5) disable/remap hotkeys that interfere with eq. go to system prefs --> dashboard+expose - disable all the hotkeys in there. then go to system prefs --> keyboard --> keyboard shortcuts and disable all the ones that will overlap with EQ hotkeys or ones that you might accidentally press.
6) boxing multiple characters on the same box. if 10.4, download VirtueDesktops. if 10.5, download VirtueDesktops. if 10.6, use Spaces (which is built-in) and disable the sliding animation.
7) alt tab on mac is command tab. unfortunately, command tab on mac sucks balls and doesn't properly switch to applications that are minimized, so you won't be using it in the same way that you do on a PC. also, there is no way to remap it to alt-tab. thanks apple! (know that the osx expose feature is an alternative to command tab, but it also has a bunch of downfalls like not working from within EQ and not working with VirtueDesktops, but you can play around with it)
8) depending on your setup (like if your mac is going to sit at the same desk your PC is), consider buying a KVM, akahttp://www.newegg.com/Product/Product.a ... th%20Audio